Product Name: Propylene Glycol BIO
Synonyms: 1,2-Propanediol, Propane-1,2-diol
CAS Number: 57-55-6
Recommended Use: Solvent, Humectant, Food Additive, Pharmaceutical Ingredient, Antifreeze
Manufacturer Details: Provided by supplier
Contact Information: Supplier phone number and emergency contact available upon request
Emergency Number: Available through local distributor
Classification: Not classified as hazardous according to OSHA HazCom 2012
Label Elements: None required under GHS
Signal Word: None
Hazard Statements: Generally recognized as safe; may cause mild eye irritation
Precautionary Statements: Avoid contact with eyes; wash hands after handling
Potential Health Effects: Low toxicity, mild irritant for eyes and skin based on human experience and animal studies
Chemical Name: Propylene Glycol
Synonyms: 1,2-Propanediol
Content: 99–100%
CAS Number: 57-55-6
Impurities: Trace amounts of water and other glycols may be present
Eye Contact: Rinse immediately with water for several minutes, remove contact lenses, continue rinsing if irritation persists, seek medical advice if necessary
Skin Contact: Wash skin with soap and water, remove contaminated clothing, rinse with water, seek medical attention if irritation develops
Inhalation: Move person to fresh air, provide oxygen or artificial respiration if breathing is difficult
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical assistance for large quantities
Immediate Medical Attention: Not normally required; observe for symptoms and treat accordingly
Suitable Extinguishing Media: Water spray, Alcohol-resistant foam, Dry chemical powder, Carbon dioxide
Specific Hazards: Combustion generates carbon monoxide and carbon dioxide, vapors may form explosive mixtures with air at elevated temperatures
Protective Equipment for Firefighters: Full protective clothing, self-contained breathing apparatus
Special Procedures: Cool fire-exposed containers with water spray, prevent runoff from entering watercourses
Personal Precautions: Wear protective gloves and goggles, avoid breathing vapors, ventilate area
Environmental Precautions: Prevent entry into waterways, drains, or soil, contain spill with sand or earth
Methods for Clean-Up: Absorb with inert material, transfer to suitable container for disposal, wash area with water to remove residues
Precautions for Safe Handling: Handle in well-ventilated space, use personal protective equipment, avoid eye and skin contact, wash thoroughly after use
Conditions for Safe Storage: Store in tightly closed containers, keep in cool, dry, well-ventilated place away from direct sunlight, segregate from strong oxidizers and acids
Specific End Uses: Avoid use near ignition sources or in unventilated areas
Exposure Limits: No occupational exposure limits established in most jurisdictions; ACGIH TWA: 10 mg/m³ (aerosol)
Engineering Controls: General ventilation recommended, use local exhaust when processing at elevated temperatures
Personal Protection: Protective gloves (nitrile or neoprene), safety glasses or goggles, appropriate clothing to prevent skin contact, respiratory protection when vapor or aerosol generation is likely
Hygiene Measures: Wash hands and face after handling, do not eat or drink while using, change contaminated clothing
Appearance: Clear, colorless, viscous liquid
Odor: Faint, sweet
Odor Threshold: Not established
pH: Neutral
Melting/Freezing Point: -60°C
Boiling Point: 187°C
Flash Point: 103°C (closed cup)
Evaporation Rate: Slow
Flammability: Not readily flammable
Explosion Limits: Lower 2.6%, Upper 12.6% (in air)
Vapor Pressure: 0.13 mmHg @ 20°C
Vapor Density: 2.6 (air = 1)
Relative Density: 1.036 g/cm³ @ 20°C
Solubility: Miscible with water, alcohol, acetone, chloroform
Partition Coefficient (log Kow): -0.92
Autoignition Temperature: 371°C
Decomposition Temperature: Not applicable
Viscosity: 58 mPa·s @ 20°C
Reactivity: Stable under recommended conditions
Chemical Stability: Does not decompose under normal storage and handling
Possibility of Hazardous Reactions: Reacts violently with strong oxidizing agents
Conditions to Avoid: Excessive heat, open flames, contact with incompatible materials
Incompatible Materials: Strong acids, strong bases, oxidizers
Hazardous Decomposition Products: Thermal decomposition yields carbon monoxide, carbon dioxide, aldehydes, acids
Acute Toxicity (Oral LD50): Rat > 20 g/kg
Skin: Not expected to cause significant irritation in intact skin; occasional mild irritation reported
Eyes: May produce mild transient conjunctival irritation
Inhalation: Minimal hazard due to low volatility
Chronic Exposure: No known long-term effects in humans or animals based on available studies
Carcinogenicity: Not classified as carcinogen by IARC, NTP, ACGIH, or OSHA
Mutagenicity: Negative in standard assays
Reproductive Toxicity: No adverse developmental effects observed in animal studies
Target Organs: None identified based on current data
Ecotoxicity: Low toxicity to aquatic organisms; LC50 (fish, 96 hr): 40,613 mg/L; EC50 (daphnia, 48 hr): 18,340 mg/L
Persistence and Degradability: Readily biodegradable under aerobic and anaerobic conditions, does not bioaccumulate
Bioaccumulative Potential: Low, log Kow indicates rapid degradation and low mobility in environment
Mobility in Soil: High solubility and low vapor pressure indicate high mobility
Other Information: Not identified as a persistent environmental pollutant, does not contribute to ozone depletion
Waste Disposal Methods: Dispose of in accordance with local, regional, and national regulations, do not discharge into surface water, sewer, or soil
Contaminated Packaging: Rinse containers before recycling, dispose of as per local hazardous waste requirements
Special Precautions: Avoid disposal in natural waterways
UN Number: Not regulated
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not assigned
Labeling Requirements: None required
Special Precautions: Protect containers from physical damage, handle with care to prevent leaks or spills
Shipping Name: Propylene Glycol
Environmental Hazards: Not a marine pollutant
US TSCA Inventory: Listed
European EINECS: 200-338-0
REACH Registration: Exempt or registered by supplier
OSHA Hazard Communication Standard: Not classified as hazardous
SARA Title III: Not listed as a hazardous chemical
California Prop 65: Not listed
Global Inventories: Present on major chemical inventories worldwide
Food and Drug Administration (FDA): Recognized as GRAS for food use in the United States
Workplace Hazards: General ventilation and basic PPE recommended for workplace safety
